{
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  "Package": "vhcub",
  "Title": "Virus-Host Codon Usage Co-Adaptation Analysis",
  "Version": "1.0.0",
  "Authors@R": "c(\nperson(given = \"Ali\",family = \"Mostafa Anwar\",role = c(\"aut\", \"cre\"),email = \"ali.mo.anwar@std.agr.cu.edu.eg\"),\nperson(given = \"Mohamed\",family = \"Soudy\",email = \"MohmedSoudy2009@gmail.com\", role = \"aut\"))",
  "Author": "Ali Mostafa Anwar [aut, cre], Mohamed Soudy [aut]",
  "Maintainer": "Ali Mostafa Anwar <ali.mo.anwar@std.agr.cu.edu.eg>",
  "Description": "Analyze the co-adaptation of codon usage between a virus\nand its host,calculate various codon usage bias measurements\nas; effective number of codons (ENc) Novembre (2002)\n<doi:10.1093/oxfordjournals.molbev.a004201>, codon adaptation\nindex (CAI) Sharp and Li (1987) <doi:10.1093/nar/15.3.1281>,\nrelative codon deoptimization index (RCDI) Puigbò et al (2010)\n<doi:10.1186/1756-0500-3-87>, similarity index (SiD) Zhou et al\n(2013) <doi:10.1371/journal.pone.0077239>, synonymous codon\nusage orderliness (SCUO) Wan et al (2004)\n<doi:10.1186/1471-2148-4-19> and, relative synonymous codon\nusage (RSCU) Sharp et al (1986) <doi:10.1093/nar/14.13.5125>.\nAlso, it provides a statistical dinucleotide over- and\nunderrepresentation with three different models. Implement\nseveral methods for visualization of codon usage as\nENc.GC3plot() and PR2.plot().",
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      "title": "Codon Adaptation Index (CAI)",
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      "title": "Statistical dinucleotide over- and underrepresentation (base model).",
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      "title": "Statistical dinucleotide over- and underrepresentation (codon model).",
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        "vhcub"
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